Willdonggang 发表于 2012-6-10 14:24:42

本帖最后由 Willdonggang 于 2012-6-11 15:59 编辑

憨叔说得对。如果病友发现其他公司其他渠道那就更好了。目前两人报名。请报名的发个电话到我的短信里。到时候统计人数,不管几个人,平均分1800元。

Willdonggang 发表于 2012-6-11 15:56:30

一种新的肿瘤标志物 AFP-L3,即使是在肝癌的早期,尤其是肿瘤组织有足够的肝动脉供给时。临床 ... 与影像学相比较,AFP-L3 在早期肝癌的诊断中可提前9-12.

veletlisa 发表于 2012-6-11 20:53:35

我报名

echojoon 发表于 2012-6-15 10:13:04

报名~

dilander 发表于 2012-6-15 23:22:29



肝癌生物标志物的一篇论文

Despite its limitations, serum AFP still remains the most widely used tumor marker in clinical practice. Recent research favors the circulating hepatoma-specific AFP subfraction AFP-L3 and DCP over AFP alone in differentiating HCC from nonmalignant hepatopathy and detecting small HCC. Furthermore, some other tumor markers, such as GPC3, GGT II, AFU, have been shown to be supplementary to AFP and DCP in the detection of HCC. Some of them even can be detected in HCC patients seronegative for both AFP and DCP, thus indicating that the simultaneous determination of these markers may improve the accuracy.

However, most exciting and promising area of research in this disease has been the identification of a new group of molecules called miRNAs. MiRNAs have been discovered to be aberrantly expressed in HCC, and some of them are functionally involved in HCC carcinogenesis and progression. Furthermore, certain microRNAs are associated with HCC or related to HCC subtypes, implicating the potential use of microRNAs in HCC patient stratification of diagnosis and prognosis. Some of these HCC-associated miRNAs have been validated in independent cohorts. This brings the possibility of developing clinically useful platforms to develop HCC diagnosis, risk assessment, and patient risk stratification with the ultimate goal of personalized therapy.

文章介绍了肝癌5类十几种标志物,认为miRNA是最有前途的肝癌评估手段。

有兴趣的可以查一下国内miRNA的进展情况。

ccl088@yahoo.cn 发表于 2012-6-16 07:36:06

我报名
,电话已经站短

Willdonggang 发表于 2012-6-16 14:38:47

现在大约有六七位病友报名,但由于试剂所限,结果的准确性可能很难判断。我想如果大家一起检测两次,结果互相参照,便更容易判断这个途径是否可以走通。
另外,除了afp,dcp,afp-L3,以外,dilander的文章说得很清楚,要多个肝癌指标同时检测互相参照,比如GPC3,GGT II,AFU.我父亲的AFU好像有一定的参考性。在AFP连续下降的时期,AFU持续上升,表明了病情发展。

另外请有意的病友发电话给我。

veletlisa 发表于 2012-6-16 16:42:30

AFU.国内一般医院有检测么

Willdonggang 发表于 2012-6-19 06:22:43

本帖最后由 Willdonggang 于 2012-6-20 16:30 编辑

veletlisa 发表于 2012-6-16 16:42 static/image/common/back.gif
AFU.国内一般医院有检测么

一般都会有。现在明确发给我电话号码报名的有4个。建议各位参加的病友每人检两次,间隔一个月。mikezx123会到上海该公司考察实际情况。

格子 发表于 2012-6-19 18:26:51

我爸的AFP很敏感,现在吃阿西有降。可还是很高。
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查看完整版本: AFP不敏感的注意,有一种指标可代替AFP用以判断病情和疗效